|
KMID : 0525720120170010005
|
|
Journal of Chitin and Chitosan
2012 Volume.17 No. 1 p.5 ~ p.7
|
|
|
The Effect of Low Molecular Weight Chitosan Oligosaccharide on the Expression of E-caderin, Snail and Vimentin in MDA-MB-231 Human Breast Cancer Cells
|
|
Jang Tae-Jung
Nam Kyung-Soo
|
|
|
Abstract
|
|
|
|
Down-regulation of E-cadherin is the hallmark of the epithelial-to-mesenchymal transition (EMT), which plays important roles in cancer progression. Low molecular weight chitosan oligosaccharide (COS-L) increased E-cadherin expression and reduced Snail expression in human breast cancer cells. We suggest COS-L may inhibit EMT phenomenon in breast cancer cells.
|
|
|
KEYWORD
|
|
|
Chitosan oligosaccharide, Epithelial-to-mesenchymal transition, Breast cancer cells
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|